The action of the peptide hormone adrenocorticotropin (ACTH) to stimulate glucocorticoid production by the adrenal gland is an essential physiologic process, yet is dependent on a single unique ...

ACTH is what stimulates the adrenal glands to make and release cortisol into the bloodstream. This process is regulated as the hypothalamus and pituitary gland monitor how much cortisol is in the ...

Our research focuses on another cause of adrenal insufficiency, inherited genetic mutations. The pituitary gland controls hormone production in the adrenals through signaling in a negative feedback ...

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The hypothalamus secretes corticotropin releasing factor, which acts on the anterior pituitary, where it stimulates the secretion of adrenocorticotropin (ACTH). The adrenal glands are stimulated ...