The properties of the different IgG isotypes should be considered in developing therapeutic antibodies. To address this problem, antibody engineers introduced a serine-to-proline substitution that ...

Neither the prevalence of IgG4 antibodies nor the titres were associated with the development of asthma. The titres of IgG1 and IgG4 to P6 and PspA in fact had a consistently positive correlation (r=0 ...

with ADC (JSKN003). Envaforlimab is a single domain antibody fused with a human immunoglobulin class G 1 (IgG1) crystallisable fragment (Fc) fragment, which received approval for subcutaneous ...