Tolvaptan is a vasopressin receptor antagonist. Vasopressin (a.k.a. ADH or antidiuretic hormone) helps to regulate water retention by absorbing water in the collecting ducts of the nephron.

The reabsorption of water back into the blood (at the medulla) is controlled by the anti-diuretic hormone (ADH). ADH is produced by the part of the brain that monitors water levels in the blood.

The posterior pituitary gland, which extends from axonal projections originating from the hypothalamus, secretes both oxytocin and anti-diuretic hormone (ADH) or vasopressin 2. The hypothalamic ...

You can develop diabetes insipidus if you have a deficiency of or resistance to antidiuretic hormone (ADH), also known as vasopressin, a hormone responsible for keeping water levels balanced in ...