Childhood or young adult onset patients usually with acromegaly can also have mutations in the AIP gene without a known family history of pituitary adenoma. DNA (Deoxyribose Nucleic Acid) is the ...

Mutations in the aryl hydrocarbon receptor interacting protein gene (AIP) are seen in a minority (15%) of FIPA families and half of homogeneous acromegaly families have AIP mutations. Most AIP ...

The red bar represent subjects who have acromegaly/gigantism and harbour the "Irish" AIP mutation. The blue bar represents patients with acromegaly but without the AIP mutation. These findings may ...