The big Swiss pharma had been hoping for approval in patients regardless of whether they have anti-aquaporin-4 (AQP4) antibodies. But so far Roche has not produced enough data in the broader ...

Approximately 80% of all patients with NMOSD test positive for anti-AQP4 antibodies. During the phase 3 trial, MRI imaging was conducted on the spinal cord, optic nerve, and brain/brain stem to ...

视神经脊髓炎谱系疾病（neuromyelitis optica spectrum disorders，NMOSD）是一组自身免疫介导的以视神经和脊髓受累为主的中枢神经系统（central nervous system，CNS）炎性脱髓鞘疾病[1]。