该研究首次发现， YTHDF2促进 B细胞恶性肿瘤的能量供应和抗原逃逸，仅其过表达就足以引起B细胞转化和肿瘤发生。更重要的是，研究团队还证实，一种名为 CCI-38的小分子能够靶向和抑制 YTHDF2，从而抑制侵袭性B细胞恶性肿瘤并提高 CAR-T 细胞疗法的效果，由此揭示了“ 小分子抑制剂+CAR-T”可能是一种治疗B细胞恶性肿瘤的有效疗法。

ATP (adenosine triphosphate) is the energy-carrying molecule used in cells because it can release energy very quickly. Energy is released from ATP when the end phosphate is removed. Once ATP has ...

生命科学Life science1月6日，来自美国德克萨斯农工大学生物化学与生物物理学系的Pingwei L教授团队在Cell Press细胞出版社旗下期刊Immunity在线发表了一篇题为“Structures of ATP-binding cassette transporter ABCC1 reveal the molecular basis of cyclic dinucleotide c ...

To emphasize this point more specifically, we also assessed ATP effects on signal output in living cells (that is, the normal test environment for FRET-based biosensors). Changes in intracellular ...

ATP, an acronym for adenosine triphosphate, provides energy to our cells, thereby aiding in the execution of physical activities. During workout sessions, our bodies deplete ATP, therefore ...

Although ATP is critically important to cells, there haven't been good ways for scientists to track how it changes in living cells. Previous ATP sensors were dim, slow, or difficult to use.

How do cells meet our bodies’ ever changing energy needs? In most animal cells, adenosine triphosphate (ATP), a compound with high potential energy, works as the main carrier of chemical energy.

In particular, they looked at the energy requirements of these cells during ischemia-reperfusion injury. Podocytes are suggested to rely on adenosine triphosphate (ATP), the main energy carrier in ...

However, the source of ATP release has not been elucidated. We measured ATP release during hypotonic stress using a real-time ATP luminescence imaging system in breast cell lines and in primary ...

S-adenosylmethionine (SAM) is a methyl group donor for most methylations in the cell and is synthesized from methionine and ATP. After methylation, SAM is converted to S-adenosylhomocysteine, which is ...

Today, even investment-grade cell tower operators in the US have four and five-year bonds trading a good 100bp wide to the levels ATP achieved in 2021. Securities with those maturities recently issued ...