No biological system has been studied by more diverse approaches than the actin-based molecular motor myosin. Biophysics, biochemistry, physiology, classical genetics and molecular genetics have ...

The actin cytoskeleton provides force for dynamic cellular processes, such as motility, morphogenesis, cell division, endocytosis, and phagocytosis. The organization and dynamics of actin filaments ...

the function of molecular machines essential to the organization and utilization of the actin and microtubule cytoskeleton of eukaryotic cells. All of the processes that we study involve dynamic ...

Filopodia help cells move but also aid cancer spread. Scientists have revealed how fascin proteins build these structures, ...

The actin filament exists as a structure of the fixed length and bears the muscle contraction and the adjustment on a muscular inside. The circulation and the molecule movements of the polymerization ...

Myosin II plays the most important role in cellular force generation. Myosin II molecules self-assemble into filaments with different structures depending on myosin II isoforms and other conditions ...

The institute harbors ~35 research groups and 250 researchers, and it operates at the highest international level. The ‘Actin-based molecular machines’ group of Academy Professor Pekka Lappalainen at ...

Actin serves many functions: it provides cells with an overall shape ... "A fascin protein can accommodate all kinds of imperfections. It acts like a molecular hinge that can hold a number of ...