Therapeutic RNA editing platforms based on this mechanism fall into one of two categories: either they use engineered enzymes, which generally consist of the editing part of the ADAR enzyme attached ...

This form of RNA editing is conducted by an enzyme called ADAR (Adenosine Deaminases Acting on RNA), altering one of the molecules within double-stranded RNA, converting it from adenosine (A ...

LEAPER uses engineered RNAs that can recruit ADAR enzymes already naturally occurring in cells, thus, minimizing side effects. Highly specific, it is more streamlined than CRISPR-Cas9. Lab tests ...