Northwestern Medicine investigators have discovered a novel mechanism that recognizes and eliminates "bad" transcriptional ...

is a genetic disorder that affects the adrenal glands, leading to hormonal imbalances due to enzyme deficiencies. The most common form of CAH is caused by a deficiency in the enzyme 21-hydroxylase ...

Crenessity (crinecerfont) is cleared as a daily oral therapy for use in patients aged four and over with classic CAH, a disease caused by a deficiency in an enzyme that stimulates the adrenal ...

it shouldn't be used in conjunction with other drugs that activate that enzyme and would thus reduce its efficacy. The drug's label also warns of acute adrenal insufficiency or adrenal crisis ...

SAN DIEGO - Neurocrine Biosciences, Inc. (NASDAQ:NBIX) has sponsored a supplement in The Journal of Clinical Endocrinology & Metabolism (JCEM) focusing on classic congenital adrenal hyperplasia (CAH), ...

Congenital adrenal hyperplasia (CAH) is a group of genetic disorders affecting the adrenal glands, which produce hormones essential for various bodily functions. One of the most common forms of ...

Adrenal steroidogenesis is under the control ... and obesity-related signals may play a role in the regulation of both enzymes involved in the steroidogenetic pathways, as well as in the ...

CAH is a rare genetic condition that results in an enzyme deficiency that alters the production of adrenal steroid hormones, such as cortisol, aldosterone and adrenal androgens, which are essential ...