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6 天
PROS1通过AKT/GSK3β/β-catenin通路抑制膀胱癌进展和血管生成的机制研究
该研究表明,PROS1 在膀胱癌中表达下调,与不良预后相关。PROS1 通过影响细胞增殖、侵袭、迁移和血管生成,在膀胱癌发展中起关键作用,其调控作用可能通过 AKT/GSK3β/β - catenin 信号通路介导。这一发现揭示了 PROS1 作为膀胱癌潜在治疗靶点的重要价值,为膀胱癌的治疗提供了新的方向。
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