Urinary Sodium and Potassium, and Aldosterone Secretion before and after Guanethidine Treatment, and Six Months after Surgical Removal of the Tumor (the Stippled Areas Represent the Normal Ranges).

Potassium and renal function must be routinely assessed to minimize the risk of life-threatening hyperkalemia. This review discusses the role of aldosterone antagonists in the treatment of heart ...

Aldosterone antagonists (spironolactone, eplerenone) also known as “potassium sparing diuretics” block the action of aldosterone inhibiting the reuptake of sodium and water. Normally ...

However, during the run-in period, one patient had to discontinue therapy because of serious hyperkalemia (serum potassium level 6.5 mmol/l) and another stopped treatment as a result of ...

potassium and volume. Aldosterone is secreted primarily by cells of the zona glomerulosa in the adrenal cortex in response to elevated levels of angiotensin II and serum potassium. Aldosterone ...

The topmost layers produce aldosterone, a hormone that signals to the kidneys to hold onto sodium while signaling the release ...

Elevated aldosterone stimulates sodium reabsorption in the cortical collecting duct as a backup mechanism of maintaining homeostasis. This mechanism results in increased potassium and hydrogen ion ...