Spironolactone inhibits the effects of aldosterone by binding to the mineralocorticoid receptor. Both insulin resistance and obesity have substantial effects on aldosterone action; 7,8 hence ...

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Between 30-50% of adults with hypertension have OSA, and this number increases to between 70-80% in adults with resistant hypertension. Additionally, untreated moderate-to-severe OSA increases the ...

In the presence of neurohormonal activation, angiotensin II causes aldosterone production in the adrenal cortex, which acts on the cortical collecting tubules to conserve sodium. Aldosterone may ...

What Is an Aldosterone Test? If you’re having any blood pressure problems, your doctor might order an aldosterone test to help them figure out what’s going on. An aldosterone test measures the ...

The team first confirmed that lack of sodium in the diet of mice increases aldosterone production and salt intake. It also increases the activity of a tiny group of neurons in the brainstem known ...