During translation, the sequence of codons is read in order from the nucleotide sequence to synthesize a chain of amino acids and form a protein. Frameshift mutations arise when the normal ...

Stop codons are also called nonsense codons because they do not code for an amino acid and instead signal the end of protein synthesis. Thus, nonsense mutations occur when a premature nonsense or ...

However, with so many amino acids in a protein, there are an astronomical number of ways mutations can combine.

The researchers mutated every single amino acid in JUN and measured the impact of each mutation on JUN's interactions with 54 different partner proteins. The mutations influenced the interactions ...