Angiotensin II has complex effects on the heart and ... Most important among these are selectivity for the angiotensin type 1 receptor and a lack of agonist activity at this receptor site.

[8,14,18,19,20] The most frequent adverse reaction, as observed in a clinical trial of 2900 patients assessing the safety and tolerability of losartan, 20 was dizziness, reported by 4.1% of ...