How does DNA recombination work ... (Note that a third model of recombination, synthesis-dependent strand annealing [SDSA], has also been proposed to account for the lack of crossover typical ...
1 Denaturation: Double-stranded DNA separates into single strands. Annealing: Short DNA fragments bind complementary regions of the template to begin new strand synthesis. Extension: Nucleotides are ...
Because DNA's makeup is determined by a simple set ... This generative design process called shape annealing was pioneered by Jon Cagan, professor of mechanical engineering.
If two homologous regions flank the DSB, they can anneal after being exposed by DNA resection (single-strand annealing; SSA), which causes the deletion of the intervening region. An additional ...
which melts double-stranded DNA into single strands; annealing, which lets small pieces of primer DNA bind to either side of the region of interest; and elongation, where the enzyme DNA polymerase ...