In the following section, the various methods used to evaluate antihistamines illustrate the developmental process for evaluating the efficacy of the H 1-receptor antagonist desloratadine.

investigated the potential of the histamine H1 blocker hydroxyzine to improve sleep in patients with cirrhosis and minimal hepatic encephalopathy. All 35 patients (mean age 56 years [range 36–69 ...

Some histamine ... antagonists or H-2 blockers. Antihistamines are available in many forms including nasal sprays, eyedrops, pills, liquids, creams, and, in more extreme cases, as inhalers or ...

For the antihistamine desloratadine, in vitro studies have revealed it to be a highly potent H 1-receptor antagonist and inhibitor of inflammatory mediators. Animal models with desloratadine have ...