In preliminary studies, we discovered that selected typical and atypical antipsychotic drugs interacted with virtually every biogenic amine receptor tested, in confirmation of many prior studies ...

Instead, both OPC-14597 and OPC-4392 exhibit clear antagonist actions at postsynaptic receptors ... some characteristics of other atypical antipsychotics with respect to induction of early ...

such as the 5-HT 1A receptor, are considered to mediate the ability of antipsychotic drugs to enhance cognition. On the other hand, treatment with some atypical agents, such as risperidone ...