Whereas the role of APOE in lipid metabolism is well characterized, the specific metabolic signatures of the APOE isoforms during metabolic disorders, remain unclear. After a 4-h fast, animals ...

Apolipoprotein E (apoE), a crucial glycoprotein in CNS lipid metabolism, particularly its apoE4 isoform, significantly influences AD pathogenesis by affecting lipid-binding properties and impairing Aβ ...

Intracellular lipid chaperones dictate the destiny of lipids. Also known as fatty acid-binding proteins (FABPs), these are a group of proteins that coordinate lipid trafficking and signalling in ...

Additionally, new research says that changes in cholesterol levels may affect your memory. American Heart Association Scientists identified Apolipoprotein E (ApoE) as the fundamental genetic cause ...

Our data show as a proof-of-principle that psychotropic drug-induced stimulation of cellular lipid biosynthesis in ... transport and -efflux, including ApoE. Such drug-effects could influence ...