Instead, I have chosen to focus on two of perhaps the most surprising and influential findings that involve the oncogene MYC ... myself. Apoptosis is a tightly regulated multi-step pathway that ...

Although these were hotly debated issues at the time, it is now clear that a multitude of signal transduction pathways and ... pressure to block MYC-potentiated apoptosis in the tumorigenic ...

it is of utmost importance to conduct research on the molecular pathways ... a consequence of MYC downregulation. Moreover, the researchers analyzed the effects of miR-377 on apoptosis ...

By selectively modulating proteins involved in these pathways, USPs contribute ... and USP7 regulate key proteins like c-Myc and p53, influencing apoptosis in BC. Similarly, autophagy, a mechanism ...