In multicellular organisms, the total number of cells is a balance between the cell-generating effects of mitosis and cell death that is induced through apoptosis. A disruption of this delicate ...

We wanted to understand how this failure – delay of cell division - activates apoptosis, and why some cancer cells may be able to avoid being killed.” Cancer cells replicate rapidly, and chemotherapy ...

The Bellis laboratory has two principal areas of research interest: Role of receptor glycosylation in conferring a stem-like, apoptosis-resistant cell phenotype Our laboratory has determined that the ...