By encapsulating curcumin within the NPs (CNPs), we enhanced their anti-inflammatory and antioxidant effects. In vivo experiments in an atherosclerotic mouse model confirmed that NPs specifically ...
Figure 1: In vivo magnetic resonance images obtained at baseline and at 1 h and 24 h postinjection of immunomicelles in ApoE −/− mice (which are prone to atherosclerotic plaques). Figure 2 ...
Atherosclerosis risk is elevated in diabetic patients, but the underlying mechanism such as the involvement of macrophages remains unclear. Here, we investigated the underlying mechanism related to ...
We hypothesise that ApoE-KO mice fed on a high fat diet, in comparison to those fed a normal diet and the wild type (non-atherosclerotic) mice, will demonstrate reduced collagen density and ...
This project combines atherosclerotic mouse models in Professor Francis’ group with state of the art multi-modal mouse neuroimaging methods that are already developed in Dr Berwick’s group in order to ...