测量乳腺癌 1 号基因相关蛋白 1（BRCA1-associated protein 1，BAP1）的表达。结果显示，MPP + 处理抑制了 SK-N-SH 细胞的增殖，促进了细胞凋亡、炎症反应和铁死亡。而 Cory 可减轻 MPP + 诱导的 SK-N-SH 细胞损伤。MPP + 会诱导 SK-N-SH 细胞中 BAP1 水平升高，Cory 处理则能缓解这 ...

This indicates that BRCA2 variants, somatic and germline, have a major role in prostate cancer progression affecting at least 1 in 10 carriers with the disease, say the researchers. BRCA1 variants ...