Mutations in the genes BRCA1 and BRCA2 can impair the body's ability to repair damage to DNA in its cells. This can greatly increase the risk of developing cancers. On average, women have a 2% ...
DNA damage is the basic cause of cancer -- but ... Patients with genetic alterations in the DNA repair genes BRCA1, BRCA2 or ATM who received olaparib had a median overall survival of 19.1 months ...