The breast cancer susceptibility gene 1 (BRCA1) protein forms complexes with other protein components to regulate the cellular response to DNA damage. Three studies now report the identification ...

RAD52 has already shown promise as a drug target. Inhibitors of the protein can selectively kill cancerous cells while ...

A University of Iowa-led study has revealed the unexpected structure adopted by the DNA repair protein RAD52 as it binds and ...

Mutations in the BRCA1 gene that are either inherited (germline) or acquired (somatic) might not be key to the initiation of prostate cancer, as previously thought, suggests the first study of its ...

Paige More got a preventive double mastectomy at age 24 after learning she was positive for the BRCA1 gene, and says it was the best decision she ever made Julie Mazziotta is the Senior Sports ...

For example the BRCA1 and BRCA2 genes that can contribute to breast cancer. Mutations in these genes account for approximately 10% of all inherited breast cancer cases detected. Scientists ...

Scientists upends scientific understanding of how anticancer drugs kill cancer Date: March 6, 2025 Source: UMass Chan Medical School Summary: BRCA1 and BRCA2 genes play a crucial role in repairing ...

Primary care doctors should assess women’s BRCA1 and BRCA2 mutation risks ... It also called for an increase in the number of cancer-specific genetic counselors in the United States.