A natural antibacterial molecule shows clinical promise. Its unusual binding site is on an excellent target: ...

but this exciting paper provides the first example of post-translational control of bacterial secretion.

Export of protein molecules across the bacterial membranes takes place via a variety of mechanisms, from simple one-component systems to complex multicomponent pathways, with five types of ...

It is really vital that we have molecular kill switches so that if someone is shedding bacteria, they do not get into the sewage system and grow. It is good to have people bringing different ...

We hope to use this new method to elucidate the evolutionary constraints on proteins that use the type III secretion system of gram negative bacteria. My newest project aims to measure the unfolding ...

Certain bacteria outcompete rivals and fend off attackers by injecting them with a lethal cocktail using tiny, nano-sized spearguns, known as type VI secretion systems (T6SS). The research group ...

The metabolite, erucamide, inhibits the virulence of pathogenic bacteria by specifically targeting the Type III Secretion (T3SS) injectisome assembly—a needle-like molecular machine used by Gram ...