Here, Dr Jamie Freeman discusses how Horizon Discovery engineers cell lines to enable deeper understanding of basic biology of disease or build better disease models. What are the key applications ...
I engineered HeLa cells to produce copious amounts of these fusion proteins, and watched where they went. Most migrated to the nucleolus, as expected, but one protein steadfastly refused. Instead, it ...
Our cell biology researchers collaborate with molecular, structural, genetic, developmental and evolutionary biologists as well as experts in genomics, genetics, virology, infectious disease, ...
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This discovery in basic cell biology has important medical implications, because mutations in Talin-1 have been linked to several diseases, such as cancer, cardiomyopathies, and hematologic disorders.
The research, in addition to its value for basic cell biology, could inform future approaches for treating or preventing problematic cell migration such as tumor metastasis. It may also relate to ...