SYMPHONY 2 (HTD1801 as an add-on therapy to Metformin): At week 24, the reduction from baseline in HbA1c with HTD1801 (-1.2%) was superior to placebo. Further, those with more severe disease had a ...

In fact, researchers have found that it has a similar blood sugar-lowering effect as the prescription drug metformin. Berberine has also decreased insulin resistance in people whose cells ...