In its cell adhesion role, β-catenin associates with the cytoplasmic domain of cadherin cell–cell adhesion proteins, such as E-cadherin (Fig. 1). Through a distinct binding site, β-catenin ...

Overholtzer et al. also noticed that before internalization, cells establish E-cadherin–beta-catenin-mediated adherens junctions and the compaction of these junctions appears to directly mediate ...