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In liver diseases, bilirubin metabolism can be altered in multiple stages. Overproduction, faulty conjugation, or defective ...
Bilirubin is a viscous, brownish-yellow substance that is a natural byproduct of liver processes like breaking down old red blood cells. Normally, it is excreted from the body without cause for ...
In addition, near-term infants have more immature hepatic mechanisms for elimination of bilirubin than their term counterparts, placing them at increased risk for elevated serum bilirubin levels.
Could jaundice be an evolutionary mechanism to protect against this? Richard got to work with an 11-strong team at the ...
Conjugation of bilirubin and delivery to the intestine doesn't necessarily lead to excretion of the substance. Neonatal intestines contain beta-glucuronidase, an enzyme capable of reducing ...