Obtain Holy Mantle for one-time protection from first damage in each room, essential for survival. Acquire items like Death's Touch to pierce enemies and Abaddon for stat boosts and special tears.

In The Binding of Isaac: Rebirth, players take Isaac on a dangerous journey through his mom's basement. As they beat floors and challenges, they'll unlock various achievements, items, and ...

The long-awaited multiplayer update to legendary roguelike The Binding of Isaac is now less than two weeks away, and the game's developer is celebrating with an additional balance pass - albeit ...

He also explained a significant balancing update will be rolled out at the same time, which will buff items players think are ...