Bone mass and strength are maintained by the bone remodeling cycle involving the integrated actions of osteocytes, osteoclasts and osteoblasts. Current therapies for the prevention and treatment ...

When someone has Paget’s disease, it means the process of bone remodeling, which is the cycle of bone growth, has become abnormal. The result is that over time, bones can become larger ...

Instead, the abnormal cycle of bone growth is managed with medications. These include bisphosphonates and calcitonin, which slow bone remodeling. Pain medications may be used to ease discomfort ...