The C1 complex is the first component of the classical complement pathway, and consists of three subunits, C1q, C1r, and C1s. The formation of an antigen–autoantibody complex is the principal ...

The role of the classical and lectin complement pathways in GI/R injury was evaluated using C1q-deficient (C1q KO), MBL-A/C-deficient (MBL-null), complement factor 2- and factor B-deficient (C2/fB ...