The results of Phase III trials of the CD20-targeted human monoclonal antibody (mAb) ofatumumab in rheumatoid arthritis and non-Hodgkin's lymphoma (NHL) dampen hopes on the potential of the drug ...

Other companies are developing CD3xCD20 bispecifics as well, including Roche's mosunetuzumab and CD20-TCB and Regeneron's REGN5678, which are already in clinical trials, although AbbVie is thought ...