Complementary discoveries have the potential to enhance treatment options for antibiotic-resistant infections. Researchers at ...
该研究对用于 CRISPR 基因编辑治疗的 Cas 核酸酶 SaCas9 和 AsCas12a 进行了理性工程化改造,设计出了具有最小化免疫原性的 SaCas9 和 AsCas12a 突变体。
Bacteria can fend off viral infections by chopping up their DNA with their CRISPR-based immune system, but sufficient numbers of phages can overwhelm microbes’ defenses. In two papers published in ...
View Full Profile. Learn about our Editorial Policies. We can target harmful bacteria. We can engineer beneficial bacteria. We can use CRISPR to study microbial interactions. We can use CRISPR to ...
Efficient and site-specific genome engineering can be achieved based on programmable nucleic acid cleavage using CRISPR-Cas surveillance complexes. Structure-function studies on single component Cas ...
CRISPR is a technology that can be used to edit genes and, as such, will likely change the world. The essence of CRISPR is simple: it’s a way of finding a specific bit of DNA inside a cell.
Our group applies structural (cryo-EM, x-ray crystallography and NMR), biochemical and biophysical methods together with functional studies to investigate macromolecular-mediated recognition, ...
ZUG, Switzerland and BOSTON, Jan. 13, 2025 (GLOBE NEWSWIRE) -- CRISPR Therapeutics (Nasdaq: CRSP), a biopharmaceutical company focused on creating transformative gene-based medicines for serious ...
CRISPR Therapeutics AG is a gene editing company, which engages in the development of transformative gene-based medicines for serious diseases using its proprietary CRISPR/Cas9 platform.