such as E-cadherin (Fig. 1). Through a distinct binding site, β-catenin also binds to the unrelated protein α-catenin, which in turn binds to filamentous actin. Thus, β-catenin provides the ...

A new study shows how an anticancer drug triggers an "outside in" signal that gets it sucked into a cancer cell. The work, published Jan. 29 in Nature Communications, reveals a new signaling mechanism ...

OnCusp Therapeutics receives US FDA fast track designation for CUSP06 for treatment of platinum-resistant ovarian cancer: Princeton, New Jersey Saturday, February 15, 2025, 15:00 ...