While the aforementioned studies show clear evidence of field cancerization, the mechanisms by which clones spread and produce a tumorigenic mutant field are not well understood. In glandular ...

2 Centre for Digestive Diseases, Blizard Institute of Cell & Molecular Science, Barts & the London School of Medicine & Dentistry, London, UK Field cancerization is defined as the preconditioning ...

"These findings suggest possible benefits of ICI therapy on field cancerization and the occurrence of cSCCs," they added. ICIs are approved to treat a range of advanced cancers, including ...