The O-specific polysaccharide of Klebsiella pneumoniae in patients with bloodstream infections is immunogenic, and its closely related subtypes are cross-reactive.

Vaccines using the immune response to the capsular polysaccharide provide effective, serogroup-specific protection against invasive disease. Vaccines based on the plain polysaccharide of the ...

The polysaccharide vaccine consists of purified capsular polysaccharides from the 23 serotypes causing about 90% of invasive pneumococcal infection in industrialized countries. Responses are age ...

pneumoniae express either the O1 or O2 antigen. In addition to the O-type, the type of polysaccharide capsule present on the surface of K. pneumoniae can also provide important insights into the ...