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But after two placebo-controlled trials, Orphan found that medically formulated GHB, sodium oxybate (Xyrem), reduced the median number of cataplexy episodes per week by 68.6%. The drug had a ...

This isn’t the case when you have narcolepsy with cataplexy. Narcolepsy is a chronic condition that happens when you don’t have enough neurons that make orexins. People with narcolepsy are ...