论文通讯作者、EMBL高级科学家Jan Ellenberg说，“我们的最新论文标志着我们理解细胞如何将染色体打包以准确分配到子细胞中的一个里程碑。这将是了解重新调整基因组以实现忠实遗传的分子机制的基础，从而合理预测如何在未来预防这一过程中出现导致人类疾病的错误。”（ 生物谷 Bioon.com） ...

Among the many marvels of life is the cell's ability to divide and thus enable organisms to grow and renew themselves. For ...

EMBL scientists have shown how overlapping loops of DNA stack upon each other in dividing cells to give rise to rod-shaped ...

Scientists at EMBL have captured how human chromosomes fold into their signature rod shape during cell division, using a ...

但3月24日发表在《Cell》杂志上的突破性研究“Nanoscale DNA tracing reveals the self-organization mechanism of mitotic chromosomes”，却彻底颠覆了我们对染色体形成的认知。 想象一下，你试图将一根细长的意大利面条塞进一个狭小的瓶子里，这看似不可能的任务，细胞却能巧妙 ...

For this, the cell must duplicate its DNA – its genome – and segregate it equally into two new daughter cells. To prepare the 46 chromosomes of a human cell for transport to the daughter cells ...

现在，EMBL科学家第一次使用一种新的染色质追踪方法在显微镜下以高分辨率直接观察到这一过程。这项新的研究表明，在细胞分裂过程中，每条染色体的长DNA分子形成了一系列相互排斥的重叠环。由于这种排斥，DNA环然后堆叠形成棒状染色体。

Utrecht University has appointed Bas van Steensel as Special Professor of Chromosome Biology. Van Steensel will lead fundamental research into how chromosomes function and how genetic information is ...

DNA analysis is crucial for identifying individuals and their relatives, using technologies like PCR, electrophoresis, and ...

Cell aging has always been an important topic in biological research, and telomere shortening is one of the key issues in ...

Genomic changes in the infectious yeast Candida tropicalis may play a role in its resistance to antifungals, according to a ...