We argue that irreversible transitions in the cell cycle (or in any other molecular control system) cannot be attributed to a single molecule or reaction, but that they derive from feedback ...

To understand such a complex system we will have to develop a new approach that will allow us to integrate the multitude of signal transduction pathways that control the cell cycle. Mathematical ...

The first part of the system is 3D, time-lapse microscopy ... Through statistical analysis of individual cell cycles in wild type embryogenesis, we found that the pace/length of cell cycle is under ...