These `cells' within cells represent an attractive model system for studies of the membrane translocation and assembly of proteins. Mitochondria are derived from endosymbiotic bacteria. During ...

Whether it be in the cell envelope of bacteria or the cytosol of eukaryotes, copper availability in cellular compartments is tightly regulated by specific metal-binding sites in trafficking proteins.

A research team from the International Research Center for Medical Sciences (IRCMS) at Kumamoto University has identified a ...

A team of researchers in Kumamoto University uncovered a previously unrecognized role of mitochondrial protein synthesis in ...

When DNA leaks out into the fluid component of the cell known as the cytosol, it means that something is wrong. "Cytosolic DNA is a danger signal associated with infections, cellular stress ...

Therapies comprising several constructs are being explored to expand the druggable sites of the human genome. “Unfortunately, estimates suggest that only 1% or less of the NA cargo that enters the ...

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However, Tan and his team wanted to identify other transcription factors regulated by STING. On screening human cells to identify proteins that shuttled from the cytosol to the nucleus during STING ...