For each structural strain of tau fibrils, they identified amino acids without which the strain cannot form its signature ...

For example, with the power of siRNA and shRNA ... with consequential and consistent differences in functional effects in cell-based assays, make for excellent controls. Principles 2 and 3 are ...

hTERT-immortalized primary cells solve the problem of limited biological relevancy in cell-based assays · hTERT-immortalized primary cells exhibit the growth characteristics of a continuous cell ...

label-free confocal imaging for live and kinetic investigations High throughput improves efficiency Reliable and proven technology Following the requirement for cell-based assay and phenotypic ...

For example, researchers will measure cell death to determine a drug’s anticancer effectiveness. Scientists commonly use caspase assays to evaluate apoptosis, evaluating caspase activation—a hallmark ...