Emerging evidence suggests that additional cell-death pathways are crucial for the triggering of inflammation and immunity. To begin to understand the contribution of cell death to immunity ...

The LNP-mRNA modality is a novel approach that uses lipid nanoparticles to deliver messenger RNA into cells. The mRNA acts as ...

A phase 1 study of a personalized cancer vaccine demonstrated antitumor immunity in all treated patients with resected renal ...

Induces potent and long-lasting immune responses to defined antigens or whole pathogens (particles), mainly through the ...

Immunizing the host with a piece of viral DNA rather than an antigenic protein fragment of the virus, helps to stimulate the generation of cell-mediated immunity (Fig. 2). DNA vaccines contain the ...

and adaptive immunity, mediated by T and B cells to protect the host from a specific pathogen or toxin. Dendritic cell subtypes work in concert to activate each other and trigger different immunol ...

T cell lymphocytes play a critical role in cell-mediated processes that underlie adaptive immunity. In this article, we focus on CD8+ T cells by characterizing their immunological phenotypes and the ...

An antibody is a component of humoral immunity. Antibodies can be effective defenders against both bacteria and ... A lipid (fatty) covering that surrounds a viral particle. It is derived from the ...

The team found that T RM cells rely on mitochondrial activity for development and are inhibited by nutrient-sensing pathways ...

More information: Siyu Pei et al, Age-related decline in CD8+ tissue resident memory T cells compromises antitumor immunity, Nature Aging (2024). DOI: 10.1038/s43587-024-00746-5 Provided by ...