It may be possible to use chemokine receptor stimulation as a means to limit entry of T cells into specific sites of ongoing stimulation such as autoimmune processes or organ transplantation.

The chemokine receptors CCR5 and CXCR4 are the two major coreceptors for HIV entry. Numerous efforts have been made to develop a new class of anti-HIV agents that target these coreceptors as an ...

To this end, we employed flow cytometry-based screening to quantify the surface expression of major chemokine receptors and integrins. A significantly increased expression of CXCR3, CXCR4 ...

Chemokines are a subclass of cytokines, a large family of small secreted proteins that communicate via G protein-coupled heptahelical chemokine receptors on the cell surface. Atrial fibrillation ...

Their findings, published in Molecular Cell, provide new insights into the receptor’s function and could contribute to the development of targeted therapies. CXCR2, a chemokine receptor ...

Equities researchers at HC Wainwright lifted their Q1 2025 EPS estimates for RAPT Therapeutics in a note issued to investors ...

Atypical chemokine receptor 1 on nucleated erythroid cells regulates haematopoiesis Nat Immunol 18:753-761, 2017. * Reviewed in F1000, IF: 21.5. Ulvmar MH, Braun A, Werth K, Kelay P, Hub E, Eller K, ...