Chemokines and their receptors help direct cell migration to sites of inflammation. You heard it here--chemokine receptors and ligands are in. Inflammation, cancer, asthma, rheumatoid arthritis, ...

“The overall conclusion is that, through one innate immune receptor, with two different ligands, you can trigger two different types of outcome.” LPS, also known as endotoxin, is a molecule found in ...

University of California has described tropane derivatives acting as 5-HT2 and muscarinic receptor ligands reported to be useful for the treatment of psychiatric disorders, depression, ...

Researchers from Astrazeneca plc and Karolinska Institutet have described the positron emission tomography (PET) evaluation of [11C]AZD-2423, a chemokine receptor type 2 (CCR2) radioligand in ...

Timothy Clark. During his PhD, Lampros focused on synthesizing allosteric modulators for the human chemokine receptor CXCR3; a G protein coupled receptor known to be involved in multiple autoimmune ...

MIP-1α specifically bound to CCR5-expressing cells and not to control cells expressing another chemokine receptor ... proteoliposomes to identify ligands from libraries of recombinant proteins ...