A new Drosophila collection of Parkinsonism models reveals early synaptic cholinergic projection neuron dysfunction, linking synaptic failure to later dopaminergic decline, highlighting a role for ...

Drugs acting on the cholinergic system can improve or worsen cognitive abilities, and their effects are particularly pronounced in frail elderly individuals and patients with Alzheimer disease.

The research team pinpointed the role of striatal cholinergic interneurons in nicotine withdrawal symptoms. Through experiments on mice, they selectively inhibited sodium channel expression in the ...

This will also dictate where you experience symptoms of excessive sweating. Primary focal hyperhidrosis occurs when the cholinergic receptors on your eccrine glands become overactivated.

Although compounds with a combined cholinergic–glutamatergic action have been trialed, none has yet been successful in the later stages of development (Table 4). Consequently, combination ...

Cold urticaria occurs after exposure to cold temperatures, while cholinergic urticaria is triggered by sweat from increased body temperature. Despite similar symptoms, these conditions differ ...