These signatures not only characterize the types of chromosomal alterations but also predict responses to specific cancer treatments, highlighting the potential for personalized medicine ...

CIN refers to an increased rate of chromosomal alterations, which can lead to diseases such as cancer. Micronuclei are small, extra nuclei that form when chromosomes or fragments of chromosomes ...

Could science help prevent birth defects? This National Birth Defects Awareness Month, here's the breakthrough every couple ...

Often referred to as "the opposite of autism," Williams syndrome is a rare genetic condition caused by the deletion of about ...

While sequencing DNA purified from bulk tumor samples enables a much more detailed look at the exact genetic code of the chromosomes, this tactic fails to provide a map of how alterations in DNA ...

[44] Patients carrying no or only numerical chromosomal alterations (group 1) Patients with exclusive structural alterations without MNA (group 2) Patients with both numerical and structural ...

Other alterations, largely present in late-stage patients, uncovered genes involved in cell cycle regulation, telomere maintenance, and DNA damage repair. Chromosomal arm-level alterations differed ...