The prognostic impact of an indication of chromosomal instability (CIN) is evaluated in a consecutive series of 952 colorectal cancer patients treated at Aker University Hospital, Norway, ...

Chromosomal instability plays a crucial role in the progression of cancer: it shapes the properties of tumor cells and drives the development of therapy resistance. Scientists from the German ...

The phenomenon that produces such genomic chaos is known as chromosomal instability (CIN). Cancer researchers and clinicians have long appreciated CIN as a hallmark of advanced and metastatic cancers; ...

Reactive oxygen species (ROS) from mitochondria are key drivers of genetic chaos in cancer by causing the collapse of micronuclear envelopes, a process that fuels the chromosomal instability (CIN ...

Dr Tatini Rakshit, Assistant Professor, Department of Chemistry, School of Natural Sciences, Shiv Nadar University, highlights how innovative approaches like chromosome analysis and AFM could signific ...