Chromosomal instability (CIN) and the frequency of micronuclei are important indicators of cellular health and can provide insights into various health conditions. CIN refers to an increased rate ...

Chromosomal instability (CIN) is a significant characteristic of many cancers, marked by the presence of large-scale changes in the number and structure of chromosomes. This instability can lead ...

In cells with high levels of chromosomal instability (in red), activation of the apoptotic caspases (in green) plays a fundamental role in tissue invasiveness. Disclaimer: AAAS and EurekAlert!

The paper S.F. Bakhoum et al., “Chromosomal instability drives metastasis through a cytosolic DNA response,” Nature, 553:467-72, 2018. Aneuploidy—the presence of abnormal numbers of chromosomes in a ...