The length of these kinetochore-attached microtubules then decreases during mitosis, pulling sister chromatids to opposite poles of the spindle. Other spindle fibers do not attach to chromosomes ...

For a living cell to divide successfully, each daughter cell must inherit the correct genetic material. In eukaryotes, segregation of duplicated chromosomes is performed by the mitotic spindle, a ...

When the microneedle was retracted, the chromosomes dropped the microtubules within 16 minutes, reorientated and then bound microtubules from opposite poles. Crucially, Nicklas then repeated the ...

Examples of questions to ask students: What might happen if chromosomes were attached to only one kinetochore? How would this affect what metaphase might look like? Looking at the cytoskeleton spindle ...

These spindle microtubules are responsible for pulling ... into the function of the centromere and its role in erroneous chromosomal segregation. To investigate the centromere structure, the ...

Microtubules emanate from the centrosomes and attach to the kinetochores of the chromosomes. These microtubules are crucial ...

These events are not mutually exclusive, nor are they independent, as each of these only serves to fuel chromosomal chaos. When microtubules from each pole of a dividing cell attach to a single ...

As the cells prepare to divide, the DNA assembles into chromosomes. Normally, microtubules latch onto these chromosomes via each chromosome’s kinetochore proteins. However, some DNA fragments lack ...